Projektbereiche

© Copyright: Jan Michael Hosan, Hessen schafft Wissen

Project Areas

The LOEWE Research Cluster iNAPO is divided into four project areas. They carry out fundamental work on design, construction, functional understanding and integration in technical devices of ion-conducting nanopores in modified polymers.

 

Project Areas iNAPO:

TP1 Engineering of Solid-State Pores

Project area 1 develops methods to introduce nanopores in polymer films with a combination of ion track technology and chemical etching. These synthetic nanopores are subjected to different organic chemical modifications to gain sensory properties. In particular they can serve as a platform for biological nanopores with high sensitivity and selectivity. These membranes are to be integrated by Micro-Nano-Integration (MNI) technology in a lab-on-chip device.

TP2 Engineering of Biological Pores

In project area 2 proteins are modified by genetic and protein engineering so that they have new sensor and switching characteristics. Cooperation between project areas 1 and 2 should lead to a stable integration of biological pores into the solid-state pores and /or that protein components for switching or sensing can be used in solid-state pores.

TP3 Transport through Porous Materials

Project area 3 uses high resolution NMR methods and theoretical approaches to analyze fundamental physico-chemical principles for ion transport in porous materials and the interaction of ions with material interfaces. The results from project area 3 will be used to design pores in the project areas 1 and 2.

TP4 Micro-Nano Integration

In project area 4 already existing pore systems and new systems, that are developed in the other project areas, are coupled to microelectronic systems to register electrical signals on a miniature scale.